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- In situ immunostaining for antibody detection
- Determine if a specific protein is associated with chromatin
- Perform specific protein sorting for mitotic and meiotic chromosomes
- Study Protein-protein interactions (in situ)
- Trace the specific binding between a particular region of the genome and the protein complex
Figure 6. Example of nuclear protein detected by antibody staining.
Left: immunostained image
Right: DAPI image showing nuclei
Figure 8: DNA-Protein Co-Detection.
DNA-Protein in situ co-detection of mouse meiotic chromosomes.
The green color represents the protein structure -- synaptonemal complex and
the red color represents telomeric DNA.
Figure 9: An example of a specific region detected by antibody within the nucleus.
- Ye J, Lu W, Moens P, Liu G, et al.
The combination of SKY and specific loci detection with FISH or Immunostaining.
Cytogenetics and Cell Genetics 93: 195-202 2001.
For more references, please check out the publications in the reliability section.
