GeneMapping | TransgeneAnalysis | CellLine Characterization | GeneTherapy | FiberFISH | AntibodyDetection | Tissue Section

	HOME PROFILES WHY US RELIABILITY CATALOG ORDER SAMPLE PREP DATA PROVIDED CONTACT US On-Line Technical Support		RELIABILITY Over 3000 novel genes and specific DNA probes have been mapped by SeeDNA. Over 95% of all the cDNA probes submitted to SeeDNA have been successfully mapped. Hundreds of cell lines have been characterized Hundreds of papers have been published by using SeeDNA's service. Please find some publications in different journals as follows: Cao X, Kambe F, Miyazaki T, et al. Novel human ZAKI-4 isoforms: hormonal and tissue-specific regulation and function as calcineurin inhibitors BIOCHEM J 367: 459-466 Part 2 OCT 15 2002 Watson PA, Kim K, Chen KS, et al. Androgen-dependent mammary carcinogenesis in rats transgenic for the Neu proto-oncogene CANCER CELL 2 (1): 67-79 JUL 2002 Mertsching E, Wurster AL, Katayama C, et al. A mouse strain defective for alpha beta versus gamma delta T cell lineage commitment INT IMMUNOL 14 (9): 1039-1053 SEP 2002 Masumoto N, Chen J, Sirotnak FM Regulation of transcription of the murine gamma-glutamyl hydrolase gene. Delineation of core promoter A and the role of LYF-1, E2F and ETS-1 in determining tumor-specific expression GENE 291 (1-2): 169-176 MAY 29 2002 Ouyang YB, Crawley JTB, Aston CE, et al. Reduced body weight and increased postimplantation fetal death in tyrosylprotein sulfotransferase-1-deficient mice J BIOL CHEM 277 (26): 23781-23787 JUN 28 2002 Kobayashi Y, Ohshiro N, Shibusawa A, et al. Isolation, characterization and differential gene expression of multispecific organic anion transporter 2 in mice MOL PHARMACOL 62 (1): 7-14 JUL 2002 Song S, Leung KKH, Pelling AL, et al. Circling, deafness, and yellow coat displayed by yellow submarine (Ysb) and light coat and circling (Lcc) mice with mutations on chromosome 3 GENOMICS 79 (6): 777-784 JUN 2002 Shekhar MPV, Lyakhovich A, Visscher DW, et al. Rad6 overexpression induces multinucleation, centrosome amplification, abnormal mitosis, aneuploidy, and transformation CANCER RES 62 (7): 2115-2124 APR 1 2002 Dijkmans J, Xu J, Masure S, et al. Characterization of platelet-derived growth factor-C (PDGF-C): expression in normal and tumor cells, biological activity and chromosomal localization INT J BIOCHEM CELL B 34 (4): 414-426 APR 2002 Boschan C, Borchert A, Ufer C, et al. Discovery of a functional Retrotransposon of the murine phospholipid hydroperoxide glutathione peroxidase: Chromosomal localization and tissue-specific expression pattern GENOMICS 79 (3): 387-394 MAR 2002 Nomoto H, Oohashi T, Hirakawa S, et al. Human BRAL1 and BCAN genes that belong to the link-module superfamily are tandemly arranged on chromosome 1 q21-23 ACTA MED OKAYAMA 56 (1): 25-29 FEB 2002 Nakabayashi K, Fernandez BA, Teshima I, et al. Molecular genetic studies of human chromosome 7 in Russell-Silver syndrome GENOMICS 79 (2): 186-196 FEB 2002 Schmid C, Heng H, Rubin C et al Sperm nuclear matrix of the PRM1-PRM2-TNP2 domain is independent of ALU methylation. Hum Mole Reproduction 7: 903-911 2002 Nicholson RH, Nicholson AW Molecular characterization of a mouse cDNA encoding Dicer, a ribonuclease III ortholog involved in RNA interference MAMM GENOME 13 (2): 67-73 FEB 2002 Kim DK, Kanai Y, Matsuo H, et al. The human T-type amino acid transporter-1: Characterization, gene organization, and chromosomal location GENOMICS 79 (1): 95-103 JAN 2002 Wang TT, Hopkins DA, Fan LQ, et al. A p53 homologue and a novel serine proteinase inhibitor are over-expressed in lung squamous cell carcinoma LUNG CANCER-J IASLC 34 (3): 363-374 DEC 2001 Leach R, Duniec-Dmuchowski Z, Tanaka T, et al. Assignment of OVCOV1 (alias CGI-15) to human chromosome 20 band q13.1 -> q13.2 by fluorescent in situ hybridization CYTOGENET CELL GENET 94 (3-4): 252-253 2001 Heng, HHQ, Liu G, Lu W, et al Multicolor SKY painting of mouse meiotic chromosomes Genome 44: 293-298. 2001 Wang TT, Fan LQ, Watanabe Y, et al. L552S, an alternatively spliced isoform of XAGE-1, is over-expressed in lung adenocarcinoma ONCOGENE 20 (53): 7699-7709 NOV 22 2001 Heng HHQ, Krawetz SA, Lu W, et al. Re-defining the chromatin loop domain CYTOGENET CELL GENET 93:155-161 (2001) Fujioka Y, Taira T, Maeda Y, et al. MM-1, a c-Myc-binding protein, is a candidate for a tumor suppressor in leukemia/lymphoma and tongue cancer J BIOL CHEM 276 (48): 45137-45144 NOV 30 2001 Ishimitsu T, Hosoya K, Tsukada K, et al. Chromosomal sublocalization and microsatellite DNA polymorphism of human adrenomedullin gene PEPTIDES 22 (11): 1739-1744 NOV 2001 Lorenza M, Khan R, Wang Y, et al. Human endothelin converting enzyme-2 (ECE2): characterization of mRNA species and chromosomal localization BIOCHIMICA ET BIOPHYSICA ACTA 1522: 46-52 (2001) Kitagawa H, Taoka M, Tone Y, et al. Human Glycosaminoglycan glucuronyltransferase I gene and a related processed pseudogene: genomic structutre, chromosomal mapping and characterization BIOCHEM J. 358: 539-546 (2001) Wu CL, Kirley SD, Xiao H, et al. Cables enhances Cdk2 tyrosine 15 phosphorylation by Wee1, inhibits cell growth, and is lost in many human colon and squamous cancers CANCER RES 61 (19): 7325-7332 OCT 1 2001 Cui Q, Matsusue K, Toh Y, et al. Assignment of the metastasis-associated gene (Mta1) to mouse chromosome band 12F and the metastasis-associated gene 2 (Mta2) to mouse chromosome band 19B by fluorescence in situ hybridization CYTOGENET CELL GENET 94 (3-4): 246-247 2001 Wiedmann M, Trueb B The mouse Fgfrl1 gene coding for a novel FGF receptor-like protein BBA-GENE STRUCT EXPR 1520 (3): 247-250 SEPT 21 2001 Kaminker PG, Kim SH, Taylor RD, et al. TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpression J BIOL CHEM 276 (38): 35891-35899 SEP 21 2001 Kitagawa H, Taoka M, Tone Y, et al. Human glycosaminoglycan glucuronyltransferase I gene and a related processed pseudogene: genomic structure, chromosomal mapping and characterization BIOCHEM J 358: 539-546 part 3 SEPT 15 2001 Mäkiniemi M, Hillukkala T, Tuusa J, et al BRCT Domain-containing Protein TopBP1 Functions in DNA Replication and Damage Response THE JOURNAL OF BIOLOGICAL CHEMISTRY 276: (32) 30399-30406 AUG. 10 2001 Yokota K, Takashima A, Bergstresser PR , et al. Identification of human homologue of the dentritic cell-associated C-type lecitin-1, dectin-1 GENE 272 (1-2): 51-60 JUL 11 2001 Xia W, Unger P, Miller L, et al. The Src-suppressed C kinase substrate, SSeCKS, is a potential metastasis inhibitor in prostate cancer CANCER RES 61 (14): 5644-5651 JUL 15 2001 Bhattacharjee H, Ho YS, Rosen BP Genomic organization and chromosomal localization of the Asna1 gene, a mouse homologue of a bacterial arsenic-translocating ATPase gene GENE 272 (1-2): 291-299 JUL 11 2001 Ye CY, Lu W, Liu G, et al. The combination of SKY and specific loci detection with FISH or immunostaining CYTOGENET CELL GENET 93:195-202 (2001) Narita T, Amano F, Yoshizaki K, et al. Assignment of SH3KBP1 to human chromosome band Xp22.1 -> p21.3 by in situ hybridization CYTOGENET CELL GENET 93 (1-2): 133-134 2001 Mayer H, Bauer H, Prohaska R Organization and chromosomal localization of the human and mouse genes coding for LanC-like protein 1 (LANCL1) CYTOGENET CELL GENET 93 (1-2): 100-104 2001 Heng HHQ, Krawetz SA, Lu W, et al. Re-defining the chromatin loop domain CYTOGENET CELL GENET 93:155-161 (2001) Dai K, Liew CC A Novel Human Striated Muscle RING Zinc Finger Protein, SMRZ Interacts with SMT3b via RING Domain JOURNAL OF BIOLOGICAL CHEMISTRY 276: (26) 23992-23999 JUNE 29 2001 Wiedmann M, Trueb B The mouse Fgfr11 gene coding for a novel FGF receptor-like protein BIOCHIMICA ET BIOPHYSICA ACTA 1520: 247-250 (2001) Li JP, Gong F, El Darwish K, Jalkanen M et al. Characterization of the D- Glucucuronyl C5-epimerase Involved in the Biosynthesis of Heparin and Heparan Sulfate JOURNAL OF BIOLOGICAL CHEMISTRY 276: (23) 20069-20077 JUNE 8 2001 Sturm S, Koch M, White AF Genomic organization of the gene for mouse PIASy and analysis of its promoter GENE 266: 123-130 2001 Sturbois-Balcerzak B, Stone JS, Sreenivas A et al. Structure and Expression of the Murine Phosphatidylserine Synthase-1 Gene JOURNAL OF BIOLOGICAL CHEMISTRY 276: (11) 8205-8212 MAR 16 2001 Caffrey JJ, Shears BS Genetic rationale for microheterogeneity of human diphosphoinositol polyphosphate phosphohydrolase type 2 GENE 269: 53-60 2001 Kim G, Lee T, Wynshaw-Boris A et al. Nucleotide sequence and structure of the mouse carbonic anhydrase III gene GENE 265: 37-44 2001 Laub F, Aldabe R, Friedrich V, et al. Developmental expression of mouse Kruppel-like transcription factor KLF7 suggests a potential role in neurogenesis DEV BIOL 233 (2): 305-318 MAY 15 2001 Iida R, Yasuda T, Tsubota E, et al. Cloning, mapping, genomic organization, and expression of mouse M-LP, a new member of the peroxisomal membrane protein Mpv17 domain family BIOCHEM BIOPH RES CO 283 (2): 292-296 MAY 4 2001 Mizoguchi K, Cha SH, Chairoungdua A et al. Human cystinuria-related transporter: Localization and functional characterization KIDNEY INTERNATIONAL 59 (5): 1821-1833 MAY 2001 Nelson RT, Boyd J, Gladue RP, et al. Genomic organization of the CC chemokine MIP-3 alpha/CCL20/LARC/EXODUS/SCYA20, showing gene structure, splice variants, and chromosome localization GENOMICS 73 (1): 28-37 APR 1 2001 Heng HHQ, Liu G, Lu W, et al. Spectral karyotyping (SKY) of mouse meiotic chromosomes GENOME 44: 293-298 (2001) Cha SH, Sekine T, Fukushima J, et al. Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney MOLECULAR PHARMACOLOGY 59 (5): 1277-1286 MAY 2001 Konno R Assignment of D-amino-acid oxidase gene to a human and a mouse chromosome AMINO ACIDS 20: (4) 401-408 2001 Anand M, Rush JS, Ray S, et al. Requirement of the Lec35 gene for all known classws of monosaccaride-P-doloicholdependent glycosyltransferase reactions in mammals MOL BIOL CELL 12 (2): 487-501 FEB 2001 Cannarile L, Zollo O, D'Adamio F, et al Cloning , chromosomal assignment and tissue distribution of human GILZ, a glucocorticoid hormone-induced gene CELL DEATH DIFFER 8 (2): 201-203 FEB 2001 Liu Z, Peng Jb, Mo R, et al. Rh type B glycoprotein is anew member of the Rh superfamily and a putative ammonia transporter in mammals J BIOL CHEM 276 (2): 1424-1433 JAN 12 2001 Forsell KALP, Boie Y, Montalibet J et al. Genomic characterization of the human and mouse protein tyrosine phosphate-1 B genes GENE 260: 145-153 2000 Saishin Y, Ishikawa R, Ugawa S, et al. Retinal Fascin: Functional Nature, Subcellular Distribution, and Chromosomal Localization Investigative Ophthalmology & Visual Science 41(8): 2087-2095; Jul 2000 Tateishi s, Sakuraba Y., Masuyama S, Inoue H., and Yamaizumi M. Dysfunction of Human Rad 18 Results in Defective Postreplication Repair and Hypersensitivity to Multiple Mutagens PNAS 97 (14): 7927-7932; July 5, 2000 Nait-Oumesmar B, Copperman B.B, Lazzarini R.A. Placental Expression and Chromosomal Localization of the Human Gcm 1 Gene. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 48(7):915-922; Jul 2000 Koide S.S., Wang L.F., Kamada M Antisperm antibodies associated with infertility: Properties and encoding genes of target antigens. PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE 224 (3):123-132; Jul 2000 Nakauchi J, Matsuo H, Kim DK, et al. Cloning and characterization of a human brain Na+-independent transporter for small neutral amino acids that transports D-serine with high affinity Neuroscience Letters 287(3):231-235; June 30, 2000 Rasmussen TE, Pedraza-Diaz S., Hardre R. et al. Structure of the human oxytocinase/insulin-regulated aminopeptidase gene and localization to chromosome 5q21 Eur. J. Biochem. 267:2297-2306; 2000 Schwer H, Liu LQ, Zhou L, et al. Cloning and Characterization of a Novel Human Ubiquitin-Specific Protease, a Homologue of Murine UBP43 (Usp18) Genomics 65:44-52, 2000 Kudo H, Senju S, Mitsuya H, Nishimura Y Mouse and Human GTPB2, Newly Identified Members of the GP-1 Family of GTPase. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATION 272:456-465, 2000 Y. Xie, L. Zhu, G. Zhao Assignment of type l phosphatidylinositol-4-phosphate 5-kinase (PIP5K1A) to human Chromosome bands 1q22>q24 by in situ hybridization CYTOGENET CELL GENET 88: 197-199, 2000 D.J Haile Assignment of Slc 11a3 to mouse chromosome 1 band 1B and SLC11A3 to human Chromosome 2q32 by in situ hybridization CYTOGENET CELL GENET 88: 328-329, 2000 Nocentini G, Bartoli A, Ronchetti S, et al. Gene Structure and Chromosomal Assignment of Mouse GITR, a Member of the Tumor Necrosis Factor/Nerve Growth Factor Receptor Family DNA and Cell Biology 19 (4): 205-217. 2000 Bo Li, Beat Trueb DRG represents a family of two closely related GTP-binding proteins Biochimica et Biophysica Acta 1491, 196-204 2000 Adachi K., Katsuyama M., Song S., et al. Genomic organization, chromosomal mapping and promoter analysis of the mouse selenocysteine tRNA gene transcription-activating factor (mStaf) gene Biochemical Journal 346: 45-51 February 2000 Nakajima H, Nakajima HO, Soonpaa MH, et al. Heritable lympho-epithelial thymoma resulting from a transgene insertional mutattion Oncogene 19: 32-38 2000 Rus'd AA, Ikejiri Y, Ono H, et al. Molecular cloning of cDNAs of mouse peptidylarginine deiminase type I, type III and type IV, and the expression pattern of type I in mouse Eur J Biochem 259: (3) 660-669 February 2000 Nakada Y., Taniura H., Uetsuki T., et al. Characterization and chromosomal mapping of a human necdin pseudogene Gene 245:185-191 January 2000 Faccio L, Fusco C, Chen A, et al. Characterization of a Novel Human Serine Protease that has Extensive homology to Bacterial Heat Shock Endoprotease HtrA and Is Regulated by Kidney Ischemia J Biol Chem 275(4):2581-2588 January 2000 Ishida N., Yoshioka S., Iida M., et al. Indispensibilty of Transmembrane Domains of Golgi UDP-Galactose Transporter as Revealed by Analysis of Genetic Defects in UDP-Galactose Transporter-Deficient Murine Had-1 Mutant Cell Lines and Construction of Deletion Mutants J. Biochem. 126: (6) 1107-1117 1999 Tarsounas M., Heng H.H.Q., Ye C.J., et al. Identification of the mouse B'-COP golgi component as a spermatocyte autoantigen in scleroderma and mapping of its gene Copb2 to mouse chromosome 9 Cytogenet Cell Genet 87: 201-204 1999 Leach R., Ko M., Krawetz S.A., Assignment of amyloid-precursor-like protein 2 gene (APLP2) to 11q24 by fluorescent in situ hybridization Cytogenet Cell Genet 87: (3-4) 215-216 1999 Adams JC, Zhang L cDNA cloning of human muskelin and localization of the muskelin (MKLN1) gene to human chromosome 7q32 and mouse chromosome 6B1/B2 by physical mapping and FISH Cytogenet Cell Genet 87: 19-21 1999 Hayes SE, Conner LJ, Stramm LE, et al. Assignment of pancreatic elF-2a kinase (EIF2AK3) to human chromosome band 2p12 by radiation hybrid mapping and in situ hybridization Cytogenet Cell Genet 86: 327-328 1999 Nakatsu F, Kadohira T, Gilbert DJ, et al. Genomic structure and chromosome mapping of the genes encoding clathrin-associated adaptor medium chains u1A (Ap1m1) and u1B (Ap1m2) Cytogenet Cell Genet 87: 53-58 1999 Kim M, Tezuka T, Suziki, et al. Molecular cloning and characterization of a novel cbl-family gene, cbl-c GENE 239: 145-154 1999 Caubit X., Thangarajah R., Theil T., et al. A Novel Nuclear Factor With Homology to Drosphila Dachshund shows a Dynamic Expression in the Neural Crest, the Eye, the Neocortex, and the Limb Bud DEVELOPMENTAL DYNAMICS 214: PP 66-80 1999 Nishimura K, Kashiwagi K, Matsuda Y, et al. Gene structure and chromosomal localization of mouse S-adenosylmethionine decarboxylase GENE 238: 343-350 1999 Vreken P, Kuilenburg ABP, Hamajima N, et al. CDNA cloning, genomic structure and chromosomal localization of the human BUP-1 gene encoding B-ureidopropionase Biochim et Biophys Acta 1447: 251-257 1999 Shadidy M, Caubit X, Olsen R, et al. Biochemical analysis of mouse FKBP60, a novel member of the FKPB family Biochim et Biophys Acta 1446: 295-307 1999 Karges W, Maier S, Wissmann A, et al. Primary structure, gene expression and chromosomal mapping of rodent homologs of the MENI tumor suppressor gene Biochim et Biophys Acta 1446: 286-294 1999 Xu H, Bai L, Ghishan FK, Molecular cloning, functional characterization, tissue distribution, and chromsomal localization of human, small intestinal sodium-phosphate (Na(+)-P(I)) transporter. Genomics 62: (2) PP281-284 Dec. 1, 1999 Hsu SY, Cloning of two novel mammalian paralogs of relaxin/insulin family proteins and their expression in testis and kidney. Mool Endocrinol 13: (12) PP 2163-2174 Dec. 1999 Tang P, Tsai-Morris CH, Dufau ML A Novel Gonadotropin-regulated Testicular RNA Helicase J BIO CHEM 274: (53) 37932-37940 DEC 31 1999 Stone D.M., Murone M., Luoh S.M.,et al. Characterization of the human Suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli J. Cell Science 112: (23) 4437-4448 December 1999 Penkov D., Ni R., Else C., Cloning of a human gene closely related to the genes coding for the c-myc single-strand binding proteins Gene 243: (2000) 27-36 November 1999 Wang AH, Bertos NR, Vezmar M, et al. HDAC4, a human histone deacetylase related to yeast HDA1, is a transcriptional corepressor MOL CELL BIOL 19: (11) 7816-7827 NOV 1999 Chun JY, Han YJ, Ahn KY, Psx homeobox gene is X-linked and specifically expressed in the trophoblast cells of mouse placenta DEVELOPMENTAL DYNAMICS 216: (3) 257-266 NOV 1999 Masure S, Haefner A, Wesselink JJ, et al. Molecular cloning, expression and characteristion of the human serine/threonine kinase Akt-3 EUROPEAN JOURNAL OF BIOCHEMISTRY 265: (1) 353-360 OCT 1999 Yandava CN, Pillari A, Drazen JM Radiation hybrid and cytogenetic mapping of SOCS1 and SOCS2 to chromosomes 16p13 and 12q, respectively GENOMICS 61: (1) 108-111 OCT 1 1999 Pardo LA, del Camino D, Sanchez A, et al. Oncogenic potential of EAG K+ channels EMBO JOURNAL 18: (20) 5540-5547 OCT 15 1999 Kleinbaum LA, Duggan C, Ferreira E, et al. Human chromosomal localization, tissue/tumor expression, and regulatory function of the ets family gene EHF BIOCHEM BIOPH RES CO 264: (1) 119-126 OCT 14 1999 Yamaguchi F, Yamaguchi K, Tokuda M, et al. Molecular cloning of EDG-3 and N-Shc genes from the puffer fish, Fugu rubripes, and conservation of synteny with the human genome FEBS LETT 459: (1) 105-110 OCT 1 1999 Hiroyama R, Takenawa T Isolation of a cDNA encoding human lysophosphatidic acid phosphatase that is involved in the regulation of mitochondrial lipid biosynthesis J BIOL CHEM 274: (41) 29172-29180 OCT 8 1999 Champagne N, Bertos NR, Pelletier N, et al. Identification of a human histone acetyltransferase related to monocytic leukemia zinc finger protein J BIOL CHEM 274: (40) 28528-28536 OCT 1 1999 Wang H, Miao SY, Chen D, et al. Assignment of chromosomal locus and evidence for alternatively spliced mRNAs of a human sperm membrane protein (hSMP-1) BBA-GENE STRUCT EXPR 1447: (1) 119-124 OCT 6 1999 Wong PMC, Kang A, Chen H, et al. Lps(d)/Ran of endotoxin-resistant C3H/HeJ mice is defective in mediating lipopolysaccharide endotoxin responses P NATL ACAD SCI USA 96: (20) 11543-11548 SEP 28 1999 Hu MCT, Wang YP, Qiu WR, et al. Hematopoietic progenitor kinase-1 (HPK1) stress response signaling pathway activates I kappa B kinases (IKK-alpha/beta) and IKK-beta is a developmentally regulated protein kinase ONCOGENE 18: (40) 5514-5524 SEP 30 1999 Velling T, Kusche-Gullberg M, Sejersen T, et al. cDNA cloning and chromosomal localization of human alpha(11) integrin - A collagen-binding, I domain-containing, beta(1-)associated integrin alpha-chain present in muscle tissues J BIOL CHEM 274: (36) 25735-25742 SEP 3 1999 Neame PJ, Tapp H, Grimm DR The cartilage-derived, C-type lectin (CLECSF1): structure of the gene and chromosomal location BBA-GENE STRUCT EXPR 1446: (3) 193-202 SEP 3 1999 Nonoguchi K, Itoh K, Xue JH, et al. Cloning of human cDNAs for Apg-1 and Apg-2, members of the Hsp110 family, and chromosomal assignment of their genes GENE 237: (1) 21-28 SEP 3 1999 Hildesheim J, Foster RA, Chamberlin ME, et al. Characterization of the regulatory domains of the human Skn-1a/Epoc-1/Oct-11 POU transcription factor J BIOL CHEM 274: (37) 26399-26406 SEP 10 1999 Shikama N, Lee CW, France S, et al. A novel cofactor for p300 that regulates the p53 response MOLECULAR CELL 4: (3) 3665-376 SEP 1999 Nagaya T, Chen KS, Fujieda M, et al. Localization of the human nuclear receptor corepressor (hN-CoR) gene between the CMT1A and the SMS critical regions of chromosome 17p11.2 GENOMICS 59: (3) 339-341 AUG 1 1999 Jilani A, Ramotar D, Slack C, et al. Molecular cloning of the human gene, PNKP, encoding a polynucleotide kinase 3 '-phosphatase and evidence for its role in repair of DNA strand breaks caused by oxidative damage J BIOL CHEM 274: (34) 24176-24186 AUG 20 1999 Zhou R, Wen H, Ao SZ Identification of a novel gene encoding a p53-associated protein GENE 235: (1-2) 93-101 JUL 22 1999 Sim DLC, Chow VTK The novel human HUEL (C4orf1) gene maps to chromosome 4p12-p13 and encodes a nuclear protein containing the nuclear receptor interaction motif GENOMICS 59: (2) 224-233 JUL 15 1999 Claudio JO, Liew CC, Ma J, et al. Cloning and expression analysis of a novel WD repeat gene, WDR3, mapping to 1p12-p13 GENOMICS 59: (1) 85-89 JUL 1 1999 Ritter M, Buechler C, Langmann T, et al. Genomic organization and chromosomal localization of the human CD163 (M130) gene: A member of the scavenger receptor cysteine-rich superfamily BIOCHEM BIOPH RES CO 260: (2) 466-474 JUL 5 1999 Ishida N, Yoshioka S, Chiba Y, et al. Molecular cloning and functional expression of the human Golgi UDP-N-acetylglucosamine transporter J BIOCHEM-TOKYO 126: (1) 68-77 JUL 1999 Imhof M, Trueb B Comparative cytogenetic mapping of COL14A1,the gene for human and mouse collagen XIV CYTOGENET CELL GENET 84: (3-4) 217-219 1999 Rheault P, Dufort I, Soucy P, et al. Assignment of HSD17B5 encoding type 5 17 beta-hydroxysteroid dehydrogenase to human chromosome bands 10p15 -> p14 and mouse chromosome13 region A2 by in situ hybridization: Identification of a new syntenic relationship CYTOGENET CELL GENET 84: (3-4) 241-242 1999 Bannert N, Kurth R, Baier M The gene encoding mouse interleukin-16 consists of seven exons and maps to Chromosome 7 D2-D3 IMMUNOGENETICS 49: (7-8) 704-706 JUL 1999 Nagasaki K, Maass N, Manabe T, et al. Identification of a novel gene, DAM1, amplified at chromosome 1p13.3-21 region in human breast cancer cell lines CANCER LETT 140: (1-2) 219-226 JUN 1 1999 Nagasaki K, Manabe T, Hanzawa H, et al. Identification of a novel gene, LDOC1, down-regulated in cancer cell lines CANCER LETT 140: (1-2) 227-234 JUN 1 1999 Pribnow D, Johnson-Pais T, Bond CT, et al. Skeletal muscle and small-conductance calcium-activated potassium channels MUSCLE NERVE 22: (6) 742-750 JUN 1999 Charbonneau A, Luu-The V Assignment of steroid 5 beta-reductase (SRD5B1) and its pseudogene (SRD5BP1) to human chromosome bands 7q32 -> q33 and 1q23 -> q25, respectively, by in situ hybridization CYTOGENET CELL GENET 84: (1-2) 105-106 1999 Bao SD, Chang MS, Auclair D, et al. Hrad17, a human homologue of the Schizosaccharomyces pombe checkpoint gene rad17, is overexpressed in colon carcinoma CANCER RESEARCH 59: (9) 2023-2028 MAY 1 1999 Hu MCT, Wang YP, Qiu WR Human fibroblast growth factor-18 stimulates fibroblast cell proliferation and is mapped to chromosome 14p11 ONCOGENE 18: (16) 2635-2642 APR 22 1999 Wang HY, Arden KC, Bermingham JR, et al. Localization of serine kinases, SRPK1 (SFRSK1) and SFRSK2 (SFRSK2), specific for the SR family of splicing factors in mouse and human chromosomes GENOMICS 57: (2) 310-315 APR 15 1999 Bemark M, Martensson A, Liberg D, et al. Spi-C, a novel Ets protein that is temporally regulated during B lymphocyte development J BIOL CHEM 274: (15) 10259-10267 APR 9 1999 Basyuk E, Cross JC, Corbin J, et al. Murine Gcm1 gene is expressed in a subset of placental trophoblast cells DEV DYNAM 214: (4) 303-311 APR 1999 Ma ZM, Wang XY, Nowatzke W, et al. Human pancreatic islets express mRNA species encoding two distinct catalytically active isoforms of group VI phospholipase A(2) (iPLA(2)) that arise from an exon-skipping mechanism of alternative splicing of the transcript from the iPLA(2) gene on chromosome 22q13.1. J BIOL CHEM 274: (14) 9607-9616 APR 2 1999 Lathrop W, Jordan J, Eustice D, et al. Rat osteotesticular phosphatase gene (Esp): genomic structure and chromosome location MAMM GENOME 10: (4) 366-370 APR 1999 Duan HJ, Wang YL, Aviram M, et al. SAG, a novel zinc RING finger protein that protects cells from apoptosis induced by redox agents MOL CELL BIOL 19: (4) 3145-3155 APR 1999 Wang LF, Zhu HD, Miao SY, et al. Molecular cloning and characterization of a novel testis-specific nucleoporin-related gene ARCH ANDROLOGY 42: (2) 71-84 MAR-APR 1999 Pangalos MN, Neefs JM, Somers M, et al. Isolation and expression of novel human glutamate carboxypeptidases with N-acetylated alpha-linked acidic dipeptidase and dipeptidyl peptidase IV activity J BIOL CHEM 274: (13) 8470-8483 MAR 26 1999 Omori F, Messner HA, Ye C, et al. Nontargeted stable integration of recombinant adeno-associated virus into human leukemia and lymphoma cell lines as evaluated by fluorescence in situ hybridization HUM GENE THER 10: (4) 537-543 MAR 1 1999 Zhao CQ, Nguyen T, Yusifov T, et al. Lipophilins: Human peptides homologous to rat prostatein BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMM. 256: (1) 147-155 MAR 5 1999 Hu MCT, Wang YP, Mikhail A, et al. Murine p38-delta mitogen-activated protein kinase, a developmentally regulated protein kinase that is activated by stress and proinflammatory cytokines J BIOL CHEM 274: (11) 7095-7102 MAR 12 1999 Jaquemar D, Schenker T, Trueb B An ankyrin-like protein with transmembrane domains is specifically lost after oncogenic transformation of human fibroblasts J BIOL CHEM 274: (11) 7325-7333 MAR 12 1999 Lohwasser S, Hande P, Mager DL, et al. Cloning of murine NKG2A, B and C: second family of C-type lectin receptors on murine NK cells EUR J IMMUNOL 29: (3) 755-761 MAR 1999 Li YH, Chambers J, Pang J, et al. Characterization of the mouse proteasome regulator PA28b gene IMMUNOGENETICS 49: (3) 149-157 MAR 1999 Bromme D, Li ZQ, Barnes M, et al. Human cathepsin V functional expression, tissue distribution, electrostatic surface potential, enzymatic characterization, and chromosomal localization BIOCHEMISTRY-US 38: (8) 2377-2385 FEB 23 1999 Nagai N, Tetuya Y, Hosokawa N, et al. The human genome has only one functional hsp47 gene (CBP2) and a pseudogene (pshsp47) GENE 227: (2) 241-248 FEB 18 1999 Salbaum JM Genomic structure and chromosomal localization of the mouse gene Punc MAMM GENOME 10: (2) 107-111 FEB 1999 Ohbayashi T, Kishimoto T, Makino Y, et al. Isolation of cDNA, chromosome mapping, and expression of the human TBP-like protein BIOCHEM BIOPH RES CO 255: (1) 137-142 FEB 5 1999 Marchese A, Sawzdargo M, Nguyen T, et al. Discovery of three novel orphan G-protein-coupled receptors GENOMICS 56: (1) 12-21 FEB 15 1999 Chen D, Lathrop W, Dong Y Molecular cloning of mouse Lrp7(Lr3) cDNA and chromosomal mapping of orthologous genes in mouse and human GENOMICS 55: (3) 314-321 FEB 1 1999 Tournier C, Whitmarsh AJ, Cavanagh J, et al. The MKK7 gene encodes a group of c-Jun NH2-terminal kinase kinases MOL CELL BIOL 19: (2) 1569-1581 FEB 1999 Sawzdargo M, Nguyen T, Lee DK, et al. Identification and cloning of three novel human G protein-coupled receptor genes GPR52, Psi GPR53 and GPR55: GPR55 is extensively expressed in human brain MOL BRAIN RES 64: (2) 193-198 FEB 5 1999 Bora RS, Kanamori A, Hirabayashi Y Assignment of a putative acetyl-CoA transporter gene (Acatn) to mouse chromosome band 3E1-E3 by in situ hybridization CYTOGENET CELL GENET 83: (1-2) 78-79 1998 Galiegue S, Jbilo O, Combes T, et al. Cloning and characterization of PRAX-1 - A new protein that specifically interacts with the peripheral benzodiazepine receptor J BIOL CHEM 274: (5) 2938-2952 JAN 29 1999 Underhill DA, Mullick A, Groulx N, et al. Physical delineation of a 700-kb region overlapping the looptail mutation on mouse chromosome 1 GENOMICS 55: (2) 185-193 JAN 15 1999 Takahashi N, Tuiki H, Saya H, et al. Localization of the gene coding for ROCK II Rho kinase on human chromosome 2p24 GENOMICS 55: (2) 235-237 JAN 15 1999 Hosoyamada M, Sekine T, Kanai Y, et al. Molecular cloning and functional expression of a multispecific organic anion transporter from human kidney AM J PHYSIOL-RENAL 45: (1) F122-F128 JAN 1999 Caubit X, Thangarajah R, Theil T, et al. Mouse dac, a novel nuclear factor with homology to Drosophila dachshund shows a dynamic expression in the neural crest, the eye, the neocortex, and the limb bud DEV DYNAM 214: (1) 66-80 JAN 1999 Okkels H, Rasmussen TE, Sanghera DK, et al. Structure of the human beta(2)-glycoprotein I (apolipoprotein H) gene EUR J BIOCHEM 259: (1-2) 435-440 JAN 1999 Masaki T, Sakai E, Furuta Y, et al. Genomic structure and chromosomal mapping of the human and mouse hippocalcin genes GENE 225: (1-2) 117-124 DEC 28 1998 Motoyama J, Heng H, Crackower MA, et al. Overlapping and non-overlapping Ptch2 expression with Shh during mouse embryogenesis MECH DEVELOP 78: (1-2) 81-84 NOV 1998 Osuka S, Takeda J, Nagiec MM, et al. Assignment of Sptlc2 to murine chromosome band 12, region E by in situ hybridization CYTOGENET CELL GENET 82: (3-4) 222-223 1998 Dean FB, Lian LB, O'Donnell M CDNA cloning and Gene Mapping of Human Homologs for Schizosaccharomyces pombe rad17, rad1, and hus1 and cloning of homologs from mouse, Caenorhabditis elegans, and Drosophila melanogaster GENOMICS 54: (3) 424-436 DEC 15 1998 Geiman TM, Durum SK, Muegge K Characterization of gene expression, genomic structure, and chromosomal localization of Hells (Lsh) GENOMICS 54: (3) 477-483 DEC 15 1998 Carver LA, LaPres JJ, Jain S, et al. Characterization of the Ah receptor-associated protein, ARA9 J BIOL CHEM 273: (50) 33580-33587 DEC 11 1998 Hu MCT, Tang-Oxley Q, Qiu WR, et al. Protein phosphatase X interacts with c-Rel and stimulates c-Rel/nuclear factor kappa B activity J BIOL CHEM 273: (50) 33561-33565 DEC 11 1998 Dai KS, Liew CC Characterization of a novel gene encoding zinc finger domains identified from expressed sequence tags (ESTs) of a human heart cDNA database J MOL CELL CARDIOL 30: (11) 2365-2375 NOV 1998 Liu L, Wang LN, Jia HP, et al. Structure and mapping of the human beta-defensin HBD-2 gene and its expression at sites of inflammation GENE 222: (2) 237-244 NOV 19 1998 Hu MCT, Wang YP I kappa B kinase-alpha and -beta genes are coexpressed in adult and embryonic tissues but localized to different human chromosomes GENE 222: (1) 31-40 NOV 5 1998 De Backer MD, Loonen I, Verhasselt P, et al. Structure of the human histamine H1 receptor gene BIOCHEM J 335: 663-670 Part 3 NOV 1 1998 Belluoccio D, Schenker T, Baici A, et al. Characterization of human matrilin-3 (MATN3) GENOMICS 53: (3) 391-394 NOV 1 1998 Bin OY, Lan ZD, Meadows J, et al. Human Bub1: A putative spindle checkpoint kinase closely linked to cell proliferation CELL GROWTH DIFFER 9: (10) 877-885 OCT 1998 Shindo M, Nakano H, Sakon S, et al. Assignment of I kappa B kinase beta (IKBKB) to human chromosome band 8p12 -> p11 by in situ hybridization CYTOGENET CELL GENET 82: (1-2) 32-33 1998 Izumi Y, Hirose T, Tamai Y, et al. An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3 J CELL BIOL 143: (1) 95-106 OCT 5 1998 Granneman JG, Zhai Y, Zhu ZX, et al. Molecular characterization of human and rat RGS 9L, a novel splice variant enriched in dopamine target regions, and chromosomal localization of the RGS 9 gene MOL PHARMACOL 54: (4) 687-694 OCT 1998 Matsumoto N, Laub F, Aldabe R, et al. Cloning the cDNA for a new human zinc finger protein defines a group of closely related Kruppel-like transcription factors J BIOL CHEM 273: (43) 28229-28237 OCT 23 1998 Li M, Xie YH, Kong YY, et al. Cloning and characterization of a novel human hepatocyte transcription factor, hB1F, which finds and activates enhancer II of hepatitis B virus J BIOL CHEM 273: (44) 29022-29031 OCT 30 1998 Cecconi F, Alvarez-Bolado G, Meyer BI, et al. Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development CELL 94: (6) 727-737 SEP 18 1998 Verkoczy LK, Marsden PA, Berinstein NL, et al. HBRAG, a novel B cell lineage cDNA encoding a type II transmembrane glycoprotein potentially involved in the regulation of recombination activating gene 1 (RAG1) EUROPEAN JOURNAL OF IMMUNOLOGY 28: (9) 2839-2853 SEP 1998 Lee SMY, Tsui SKW, Chan KK, et al. Chromosomal mapping, tissue distribution and cDNA sequence of four-and-a-half LIM domain protein 1 (FHL1) GENE 216: (1) 163-170 AUG 17 1998 Taira T, Maeda J, Onishi T, et al. AMY-1, a novel C-MYC binding protein that stimulates transcription activity of C-MYC GENES CELLS 3: (8) 549-565 AUG 1998 Chow VTK, Lim KM, Lim D The human DENN gene: genomic organization, alternative splicing, and localization to chromosome 11p11.21-p11.22 GENOME 41: (4) 543-552 AUG 1998 Fusco C, Reymond A, Zervos AS Molecular cloning and characterization of a novel retinoblastoma-binding protein GENOMICS 51: (3) 351-358 AUG 1 1998 Majumdar M, Datta K Assignment of cDNA encoding hyaluronic acid-binding protein 1 to human chromosome 17p12-p13 GENOMICS 51: (3) 476-477 AUG 1 1998 Zumbrunn J, Trueb B Assignment of the ZYX gene for the LIM protein zyxin to human chromosome bands 7q34 -> q35 by in situ hybridization CYTOGENET CELL GENET 81: (3-4) 283-284 1998 Waterham HR, Wijburg FA, Hennekam RCM, et al. Smith-Lemli-Opitz syndrome is caused by mutations in the 7-dehydrocholesterol reductase gene AM J HUM GENET 63: (2) 329-338 AUG 1998 Mio H, Kagami N, Yokokawa S, et al. Isolation and characterization of a cDNA for human, mouse, and rat full-length stem cell growth factor, a new member of C-type lectin superfamily BIOCHEM BIOPH RES CO 249: (1) 124-130 AUG 10 1998 Bautista S, Theillet C CCND1 and FGFR1 coamplification results in the colocalization of 11q13 and 8p12 sequences in breast tumor nuclei GENE CHROMOSOME CANC 22: (4) 268-277 AUG 1998 Collas P, Alestrom P Nuclear localization signals enhance germline transmission of a transgene in zebrafish TRANSGENIC RES 7: (4) 303-309 JUL 1998 Irie A, Suzuki A CMP-N-acetylneuraminic acid hydroxylase is exclusively inactive in humans BIOCHEM BIOPH RES CO 248: (2) 330-333 JUL 20 1998 Agulnik SI, Papaioannou VE, Silver LM Cloning, mapping, and expression analysis of TBX15, a new member of the T-box gene family GENOMICS 51: (1) 68-75 JUL 1 1998 Parker AE, Van de Weyer I, Laus MC, et al. A human homologue of the Schizosaccharomyces pombe rad1(+) checkpoint gene encodes an exonuclease J BIOL CHEM 273: (29) 18332-18339 JUL 17 1998 Parker AE, Van de Weyer I, Laus MC, et al. Identification of a human homologue of the Schizosaccharomyces pombe rad17(+) checkpoint gene J BIOL CHEM 273: (29) 18340-18346 JUL 17 1998 Salomon-Nguyen F, Le Coniat-Busson M, Heilig R, et al. Evidence of chromosomal inversion using fluorescence in situ hybridization to stretched DNA CR ACAD SCI III-VIE 321: (6) 447-452 JUN 1998 Tremblay LO, Dyke NC, Herscovics A Molecular cloning , chromosomal mapping and tissue-specific expression of a novel human alpha 1,2-mannosidase gene involved in N-glycan maturation GLYCOBIOLOGY 8: (6) 585-595 JUN 1998 Wu JG, He J, Mountz JD Effect of age and apoptosis on the mouse homologue of the huWRN gene MECH AGEING DEV 103: (1) 27-44 JUN 1 1998 Takeuchi T, Furihata M, Henry HHQ, et al. Chromosomal mapping and expression of the human B120 gene GENE 213: (1-2) 189-193 JUN 15 1998 Sam M, Wurst W, Kluppel M, et al. Aquarius, a novel gene isolated by gene trapping with an RNA-dependent RNA polymerase motif DEV DYNAM 212: (2) 304-317 JUN 1998 Wolting CD, McGlade CJ, et al. Cloning and chromosomal localization of a new member of the bHLH/PAS transcription factor MAMMALIAN GENOME 9: (6) 463-468 JUN 1998 Wolting CD, McGlade CJ, et al. Cloning and chromosomal localization of a new member of the bHLH/PAS transcription factor MAMMALIAN GENOME 9: (6) 463-468 JUN 1998 Ichikawa S, Ozawa K, Hirabayashi Y Assignment of a UDP-glucose : ceramide glucosyltransferase gene (UGCG) to human chromosome band 9q31 by in situ hybridization CYTOGENET CELL GENET 79: (3-4) 233-234 1997 Schenker T, Trueb B Assignment of the gene for a developmentally regulated GTP-binding protein (DRG2) to human chromosome bands 17p13 -> p12 by in situ hybridization CYTOGENET CELL GENET 79: (3-4) 274-275 1997 Pan YX, Mei JF, Xu J, et al. Cloning and characterization of a mouse sigma(1) receptor J NEUROCHEM 70: (6) 2279-2285 JUN 1998 Pietzsch A, Buchler C, Schmitz G Genomic organization, promoter cloning, and chromosomal localization of the Dif-2 gene BIOCHEM BIOPH RES CO 245: (3) 651-657 APR 28 1998 Fujioka M, Takahashi N, Odai H, et al. A new isoform of human myosin phosphatase targeting/regulatory subunit (MYPT2): cDNA cloning, tissue expression, and chromosomal mapping GENOMICS 49: (1) 59-68 APR 1 1998 Bartsch JW, Mukai H, Takahashi N, et al. The protein kinase N (PKN) gene PRKCL1/Prkcl1 maps to human chromosome 19p12-p13.1 and mouse chromosome 8 with close linkage to the myodystrophy (myd) mutation GENOMICS 49: (1) 129-132 APR 1 1998 Ma JX, Ramachandran S, Fiedorek FT, et al. Mapping of the CYP2J cytochrome P450 genes to human chromosome 1 and mouse chromosome 4 GENOMICS 49: (1) 152-155 APR 1 1998 de Vet ECJM, Ijlst L, Oostheim W, et al. Alkyl-dihydroxyacetonephosphate synthase - Fate in peroxisome biogenesis disorders and identification of the point mutation underlying a single enzyme deficiency J BIOL CHEM 273: (17) 10296-10301 APR 24 1998 Van den Wyngaert I, Sprengel J, Kass SU, et al Cloning and analysis of a novel human putative DNA methyltransferase FEBS LETT 426: (2) 283-289 APR 17 1998 Ohno H, Poy G, Bonifacino JS Cloning of the gene encoding the murine clathrin-associated adaptor medium chain mu 2: gene organization, alternative splicing and chromosomal assignment GENE 210: (2) 187-193 APR 14 1998 Chan KK, Tsui SKW, Lee SMY, et al. Molecular cloning and characterization of FHL2, a novel LIM domain protein preferentially expressed in human heart GENE 210: (2) 345-350 APR 14 1998 Heng HHQ, Wang AA, Hu J Mapping of the human HPRP3 and HPRP4 genes encoding U4/U6-associated splicing factors to chromosomes 1q21.1 and 9q31-q33 GENOMICS 48: (2) 273-275 MAR 1 1998 Yasuda T, Takeshita H, Iida R, et al. Chromosomal localization of a human deoxyribonuclease II gene (DNASE2) to 19p13.2-p13.1 using both the polymerase chain reaction and fluorescence in situ hybridization analysis BIOCHEM BIOPH RES CO 244: (3) 815-818 MAR 27 1998 Duell T, Nielsen LB, Jones A, et al. Construction of two near-kilobase resolution restriction maps of the 5 ' regulatory region of the human apolipoprotein B gene by quantitative DNA fiber mapping (QDFM) CYTOGENET CELL GENET 79: (1-2) 64-70 1997 Vadnal R, Heng HHQ, Parthasarathy L, et al. Human chromosomal localization of a gene for inositol monophosphatase by fluorescence in situ hybridization NEUROREPORT 9: (4) 683-685 MAR 9 1998 Leclerc D, Wilson A, Dumas R, et al. Cloning and mapping of a cDNA for methionine synthase reductase, a flavoprotein defective in patients with homocystinuria P NATL ACAD SCI USA 95: (6) 3059-3064 MAR 17 1998 Yamashita Y, Fukuta D, Tsuji A, et al. Genomic structures and chromosomal location of p91, a novel murine regulatory receptor family J BIOCHEM-TOKYO 123: (2) 358-368 FEB 1998 Kamei Y, Tsutsumi O, Taketani Y, et al. cDNA cloning and chromosomal localization of neural adhesion molecule NB-3 in human J NEUROSCI RES 51: (3) 275-283 FEB 1 1998 Masure S, Cik M, Pangalos MN, et al. Molecular cloning, expression and tissue distribution of glial-cell-line-derived neurotrophic factor family receptor alpha-3 (GFR alpha-3) EUR J BIOCHEM 251: (3) 622-630 FEB 1 1998 Snow BE, Antonio L, Suggs S, et al. Cloning of a retinally abundant regulator of G-protein signaling (RGS-r/RGS16): genomic structure and chromosomal localization of the human gene GENE 206: (2) 247-253 JAN 12 1998 Liu ISC, Kusumi I, Ulpian C, et al. A serotonin-4 receptor-like pseudogene in humans MOL BRAIN RES 53: (1-2) 98-103 JAN 1998 Kuno K, Iizasa H, Ohno S, et al. The exon/intron organization and chromosomal mapping of the mouse ADAMTS-1 gene encoding an ADAM family protein with TSP motifs GENOMICS 46: (3) 466-471 DEC 15 1997 Li Y, Asahara H, Patel VS, et al. Purification, cDNA cloning, and gene mapping of the small subunit of human DNA polymerase epsilon J BIOL CHEM 272: (51) 32337-32344 DEC 19 1997 Wigle JT, Demchyshyn L, Pratt MAC, et al. Molecular cloning, expression, and chromosomal assignment of sarcolemmal-associated proteins - A family of acidic amphipathic alpha-helical proteins associated with the membrane J BIOL CHEM 272: (51) 32384-32394 DEC 19 1997 Schmiedeknecht G, Buchler C, Schmitz G A bidirectional promoter connects the p14.5 gene to the gene for RNase P and RNase MRP protein subunit hPOP1 BIOCHEM BIOPH RES CO 241: (1) 59-67 DEC 8 1997 Nishiyama H, Higashitsuji H, Yokoi H, et al. Cloning and characterization of human CIRP (cold-inducible RNA-binding protein) cDNA and chromosomal assignment of the gene GENE 204: (1-2) 115-120 DEC 19 1997 Luk SCW, GarciaBarcelo M, Tsui SKW, et al. Assignment of the human 14-3-3 epsilon isoform (YWHAE) to human chromosome 17p13 by in situ hybridization CYTOGENET CELL GENET 78: (2) 105-106 1997 GarciaBarcelo M, Law PTW, Tsui SKW, et al. Mapping of the human ribosomal large subunit protein gene RPL29 to human chromosome 3q29-qter GENOMICS 46: (1) 148-151 NOV 1997 GarciaBarcelo M, Law PTW, Tsui SKW, et al. Mapping of the human ribosomal large subunit protein gene RPL29 to human chromosome 3q29-qter GENOMICS 46: (1) 148-151 NOV 1997 Okano K, Heng H, Trevisanato S, et al. Genomic organization and functional analysis of the murine protein phosphatase 1c gamma (Ppp1cc) gene GENOMICS 45: (1) 211-215 OCT 1 1997 Kershaw DB, Wiggins JE, Wharram BL, et al. Assignment of the human podocalyxin-like protein (PODXL) gene to 7q32-q33 GENOMICS 45: (1) 239-240 OCT 1 1997 Li FG, Liu JG, Mayne R, et al. Identification and characterization of a mouse protein kinase that is highly homologous to human integrin-linked kinase BBA-MOL CELL RES 1358: (3) 215-220 OCT 11 1997 Khaleduzzaman M, Sumiyoshi H, Ueki Y, et al. Structure of the human type XIX collagen (COL19A1) gene, which suggests it has arisen from an ancestor gene of the FACIT family GENOMICS 45: (2) 304-312 OCT 15 1997 Zumbrunn J, Trueb B Localization of the gene for a serine protease with IGF-binding domain (PRSS11) to human chromosome 10q25.3-q26.2 GENOMICS 45: (2) 461-462 OCT 15 1997 StArnaud R, Messerlian S, Moir JM, et al. The 25-hydroxyvitamin D 1-alpha-hydroxylase gene maps to the pseudovitamin D deficiency rickets (PDDR) disease locus J BONE MINER RES 12: (10) 1552-1559 OCT 1997 Nakagawa T, Tanaka Y, Matsuoka E, et al. Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome P NATL ACAD SCI USA 94: (18) 9654-9659 SEP 2 1997 Kissil JL, Kimchi A Assignment of death associated protein 3 (DAP3) to human chromosome 1q21 by in situ hybridization CYTOGENET CELL GENET 77: (3-4) 252-252 1997 Hardiman G, Kastelein RA, Bazan JF Isolation, characterization and chromosomal localization of human WNT10B CYTOGENET CELL GENET 77: (3-4) 278-282 1997 Liu LD, Zhao CQ, Heng HHQ, et al. The human beta-defensin-1 and alpha-defensins are encoded by adjacent genes: Two peptide families with differing disulfide topology share a common ancestry GENOMICS 43: (3) 316-320 AUG 1 1997 Traish AM, Huang YH, Ashba J, et al. Loss of expression of a 55 kDa nuclear protein (nmt55) in estrogen receptor-negative human breast cancer DIAGN MOL PATHOL 6: (4) 209-221 AUG 1997 Miyazato M, Nakazato M, Matsukura S, et al. Genomic structure and chromosomal localization of human uroguanylin GENOMICS 43: (3) 359-365 AUG 1 1997 Takahashi N, Ito M, Tanaka J, et al. Localization of the gene coding for myosin phosphatase, target subunit 1 (MYPT1) to human chromosome 12q15-q21 GENOMICS 44: (1) 150-152 AUG 15 1997 Kataoka M, Yoshiyama K, Matsuura K, et al. Structure of the murine CD156 gene, characterization of its promoter, and chromosomal location J BIOL CHEM 272: (29) 18209-18215 JUL 18 1997 GarciaGuzman M, Stuhmer W, Soto F Molecular characterization and pharmacological properties of the human P2X(3) purinoceptor MOL BRAIN RES 47: (1-2) 59-66 JUL 1997 Chen HI, Einbond A, Kwak SJ, et al. Characterization of the WW domain of human yes-associated protein and its polyproline-containing ligands J BIOL CHEM 272: (27) 17070-17077 JUL 4 1997 Yamamura H, Masuda H, Ikeda W, et al. Structure and expression of the human SM22 alpha gene, assignment of the gene to chromosome 11, and repression of the promoter activity by cytosine DNA methylation J BIOCHEM-TOKYO 122: (1) 157-167 JUL 1997 Lu RZ, Nash HM, Verdine GL A mammalian DNA repair enzyme that excises oxidatively damaged guanines maps to a locus frequently lost in lung cancer CURR BIOL 7: (6) 397-407 JUN 1 1997 Kwon BS, Tan KB, Ni J, et al. A newly identified member of the tumor necrosis factor receptor superfamily with a wide tissue distribution and involvement in lymphocyte activation J BIOL CHEM 272: (22) 14272-14276 MAY 30 1997 Quek HH, Chow VTK Genomic organization and mapping of the human HEP-COP gene (COPA) to 1q CYTOGENET CELL GENET 76: (3-4) 139-143 1997 Hannigan GE, Bayani J, Weksberg R, et al. Mapping of the gene encoding the integrin-linked kinase, ILK, to human chromosome 11p15.5-p15.4 GENOMICS 42: (1) 177-179 MAY 15 1997 Simonet WS, Lacey DL, Dunstan CR, et al. Osteoprotegerin: A novel secreted protein involved in the regulation of bone density CELL 89: (2) 309-319 APR 18 1997 Gotoh T, Araki M, Mori M Chromosomal localization of the human arginase II gene and tissue distribution of its mRNA BIOCHEM BIOPH RES CO 233: (2) 487-491 APR 17 1997 Yoshiyama K, Higuchi Y, Kataoka M, et al. CD156 (human ADAM8): Expression, primary amino acid sequence, and gene location GENOMICS 41: (1) 56-62 APR 1 1997 ODowd BF, Nguyen T, Jung BP, et al. Cloning and chromosomal mapping of four putative novel human G-protein-coupled receptor genes GENE 187: (1) 75-81 MAR 10 1997 Hilbert TP, Chaung WR, Boorstein RJ, et al. Cloning and expression of the cDNA encoding the human homologue of the DNA repair enzyme, Escherichia coli endonuclease III J BIOL CHEM 272: (10) 6733-6740 MAR 7 1997 Chew A, Buck EA, Peretz S, et al. Cloning, expression, and chromosomal assignment of the human mitochondrial intermediate peptidase gene (MIPEP) GENOMICS 40: (3) 493-496 MAR 15 1997 MalnarDragojevic D, Trachtulec Z, Vincek V Assignment of the mouse ligatin gene (Lgtn) to chromosome 1F by in situ hybridization GENOMICS 40: (1) 192-193 FEB 15 1997 Britton CH, Mackey DW, Esser V, et al. Fine chromosome mapping of the genes for human liver and muscle carnitine palmitoyltransferase I (CPT1A and CPT1B) GENOMICS 40: (1) 209-211 FEB 15 1997 GarciaAnoveros J, Derfler B, NevilleGolden J, et al. BNaC1 and BNaC2 constitute at new family of human neuronal sodium channels related to degenerins and epithelial sodium channels P NATL ACAD SCI USA 94: (4) 1459-1464 FEB 18 1997 Chang PWG, Tsui SKW, Liew CC, et al. Isolation, characterization, and chromosomal mapping of a novel cDNA clone encoding human selenium binding protein J CELL BIOCHEM 64: (2) 217-224 FEB 1997 Brakebusch C, Jallal B, Fusco O, et al. Expression of the 90K immunostimulator gene is controlled by a promoter with unique features J BIOL CHEM 272: (6) 3674-3682 FEB 7 1997 Powell MB, Marchbank KJ, Rushmere NK, et al. Molecular cloning, chromosomal localization, expression, and functional characterization of the mouse analogue of human CD59 J IMMUNOL 158: (4) 1692-1702 FEB 15 1997 Jung BP, Nguyen T, Kolakowski LF, et al. Discovery of a novel human G protein-coupled receptor gene (GPR25) located on chromosome 1 BIOCHEM BIOPH RES CO 230: (1) 69-72 JAN 3 1997 GarciaGuzman M, Soto F, GomezHernandez JM, et al. Characterization of recombinant human P2X(4) receptor reveals pharmacological differences to the rat homologue MOL PHARMACOL 51: (1) 109-118 JAN 1997 Fam NP, Zhang LJ, Rommens JM, et al. Mapping of the Ras-GRF2 gene (GRF2) to mouse chromosome 13C3-D1 and human chromosome 5q13, near the Res-GAP gene GENOMICS 39: (1) 118-120 JAN 1 1997 Ma WJ, Furneaux H Localization of the human HuR gene to chromosome 19p13.2 HUM GENET 99: (1) 32-33 JAN 1997 Moosmann P, Georgiev O, LeDouarin B, et al. Transcriptional repression by RING finger protein TIF1 beta that interacts with the KRAB repressor domain of KOX1 NUCLEIC ACIDS RES 24: (24) 4859-4867 DEC 15 1996 Gaedigk R, Karges W, Hui MF, et al. Genomic organization and transcript analysis of ICAp69, a target antigen in diabetic autoimmunity GENOMICS 38: (3) 382-391 DEC 15 1996 Kolakowski LF, Jung BP, Nguyen T, et al. Characterization of a human gene related to genes encoding somatostatin receptors FEBS LETT 398: (2-3) 253-258 DEC 2 1996 Lam WY, Tsui SKW, Law PTW, et al. Isolation and characterization of a human heart cDNA encoding a new member of the small heat shock protein family - HSPL27 BBA-MOL CELL RES 1314: (1-2) 120-124 NOV 8 1996 Kumar A, Toscani A, Rane S, et al. Structural organization and chromosomal mapping of JAK3 locus ONCOGENE 13: (9) 2009-2014 NOV 7 1996 Kim KK, Daud AI, Wong SC, et al. Mouse RAD50 has limited epitopic homology to p53 and is expressed in the adult myocardium J BIOL CHEM 271: (46) 29255-29264 NOV 15 1996 Xie Y, Muller WA Assignment of PECAM1 to human chromosome bands 17q22->q23 by in situ hybridization CYTOGENET CELL GENET 74: (1-2) 156-156 1996 Xie Y, Muller WA Fluorescence in situ hybridization mapping of the mouse platelet endothelial cell adhesion molecule-1 (PECAM1) to mouse chromosome 6, region F3-G1 GENOMICS 37: (2) 226-228 OCT 15 1996 Gasdaska JR, Gasdaska PY, Gallegos A, et al. Human thioredoxin reductase gene localization to chromosomal position 12q23-q24.1 and mRNA distribution in human tissue GENOMICS 37: (2) 257-259 OCT 15 1996 Yamaguchi F, Tokuda M, Hatase O, et al. Molecular cloning of the novel human G protein-coupled receptor (GPCR) gene mapped on chromosome 9 BIOCHEM BIOPH RES CO 227: (2) 608-614 OCT 14 1996 Yang BZ, Heng HHQ, Ding JH, et al. The genes for the alpha and beta subunits of the mitochondrial trifunctional protein are both located in the same region of human chromosome 2p23 GENOMICS 37: (1) 141-143 OCT 1 1996 Sam M, Wurst W, Forrester L, et al. A novel family of repeat sequences in the mouse genome responsive to retinoic acid MAMM GENOME 7: (10) 741-748 OCT 1996 Shen ZY, PardingtonPurtymun PE, Comeaux JC, et al. UBL1, a human ubiquitin-like protein associating with human RAD51/RAD52 proteins GENOMICS 36: (2) 271-279 SEP 1 1996 Gale NW, Flenniken A, Compton DC, et al. Elk-L3, a novel transmembrane ligand for the Eph family of receptor tyrosine kinases, expressed in embryonic floor plate, roof plate and hindbrain segments ONCOGENE 13: (6) 1343-1352 SEP 19 1996 Boisclair YR, Seto D, Hsieh S, et al. Organization and chromosomal localization of the gene encoding the mouse acid labile subunit of the insulin-like growth factor binding complex P NATL ACAD SCI USA 93: (19) 10028-10033 SEP 17 1996 Hasson T, Skowron JF, Gilbert DJ, et al. Mapping of unconventional myosins in mouse and human GENOMICS 36: (3) 431-439 SEP 15 1996 Vaandrager JW, Schuuring E, Zwikstra E, et al. Direct visualization of dispersed 11q13 chromosomal translocations in mantle cell lymphoma by multicolor DNA fiber fluorescence in situ hybridization BLOOD 88: (4) 1177-1182 AUG 15 1996 Li SW, Satoh H, Watanabe T, et al. cDNA cloning and chromosomal mapping of a novel human GAP (GAP1M), a GTPase-activating protein of Ras GENOMICS 35: (3) 625-627 AUG 1 1996 Tsui SKW, Chan PPK, Cheuk CW, et al. A novel cDNA encoding for a LIM domain protein located at human chromosome 14q32 as a candidate for leukemic translocation BIOCHEM MOL BIOL INT 39: (4) 747-754 JUL 1996 Takiguchi Y, Kurimasa A, Chen FQ, et al. Genomic structure and chromosomal assignment of the mouse Ku70 gene GENOMICS 35: (1) 129-135 JUL 1 1996 Wang RX, Cukerman E, Heng HHQ, et al. Localization of a novel zinc finger gene to human chromosome 7q22 region by fluorescence in situ hybridization SOMAT CELL MOLEC GEN 22: (3) 233-235 MAY 1996 Wang RX, Cukerman E, Heng HHQ, et al. Localization of three novel zinc finger genes to the centromeric region of human chromosome 10 by fluorescence in situ hybridization SOMAT CELL MOLEC GEN 22: (3) 241-244 MAY 1996 Cimprich KA, Shin TB, Keith CT, et al. cDNA cloning and gene mapping of a candidate human cell cycle checkpoint protein P NATL ACAD SCI USA 93: (7) 2850-2855 APR 2 1996 Huang WY, Heng HHQ, Liew CC Assignment of the human GATA4 gene to 8p23.1->p22 using fluorescence in situ hybridization analysis CYTOGENET CELL GENET 72: (2-3) 217-218 1996 Schmitt J, Hotten G, Jenkins NA, et al. Structure, chromosomal localization, and expression analysis of the mouse inhibin/activin beta(c) (Inhbc) gene GENOMICS 32: (3) 358-366 MAR 15 1996 Yurov YB, Soloviev IV, Vorsanova SG, et al. High resolution multicolor fluorescence in situ hybridization using cyanine and fluorescein dyes: Rapid chromosome identification by directly fluorescently labeled alphoid DNA probes HUM GENET 97: (3) 390-398 MAR 1996 Kim KK, Youn BS, Heng HHQ, et al. Genomic organization and FISH mapping of human Pmel 17, the putative silver locus PIGM CELL RES 9: (1) 42-48 FEB 1996 Coignet LJA, Schuuring E, Kibbelaar RE, et al. Detection of 11q13 rearrangements in hematologic neoplasias by double-color fluorescence in situ hybridization BLOOD 87: (4) 1512-1519 FEB 15 1996 Nguyen T, Erb L, Weisman GA, et al. Cloning, expression, and chromosomal localization of the human uridine nucleotide receptor gene J BIOL CHEM 270: (52) 30845-30848 DEC 29 1995 Marchese A, Heiber M, Nguyen T, et al. Cloning and chromosomal mapping of 3 novel genes, GPR9, GPR10, and GPR14 encoding receptors related to interleukin-8, neuropeptide-y, and somatostatin receptors GENOMICS 29: (2) 335-344 SEP 20 1995 Huang F, Shi LJ, Heng HHQ, et al. Assignment of the human GABA transporter gene (GABATHG) locus to chromosome 3p24-p25 GENOMICS 29: (1) 302-304 SEP 1 1995 Charest A, Wagner J, Muise ES, et al. Structure of the murine MPTP-pest gene - genomic organization and chromosomal mapping GENOMICS 28: (3) 501-507 AUG 10 1995 Fung YW, Wang RX, Heng HHQ, et al. Mapping of a human LIM-protein (CLP) to human-chromosome 11p15.1 by fluorescence in-situ hybridization GENOMICS 28: (3) 602-603 AUG 10 1995 Odowd BF, Scheideler MA, Nguyen T, et al. The cloning and chromosomal mapping of 2 novel human opioid-somatostatin-like receptor genes, GPR7 and GPR8, expressed in discrete areas of the brain GENOMICS 28: (1) 84-91 JUL 1 1995 Heiber M, Docherty JM, Shah G, et al. Isolation of 3 novel human genes encoding g-protein-coupled receptors DNA CELL BIOL 14: (1) 25-35 JAN 1995 Marchese A, Docherty JM, Nguyen T, et al. Cloning of human genes encoding novel g-protein-coupled receptors GENOMICS 23: (3) 609-618 OCT 1994 Dr. Henry H.Q. Heng is the founder of SeeDNA Biotech Inc.. The following is a partial list of Dr. Heng's FISH related publications: Part A:Novel FISH Detection Systems for Genome/Chromosome Research Heng, H.H.Q., Squire, J., and Tsui, L-C. (1992). High resolution mapping of mammalian genes by in situ hybridization to free chromatin. Proc. Natl. Acad. Sci. USA 89: 9509-9513. Heng, H.H.Q., and Tsui, L-C. (1993). Modes of DAPI banding and simultaneous in situ hybridization. Chromosoma 102: 325-332. Heng, H.H.Q., and Tsui, L-C. (1994). Chapter 10: Free chromatin mapping by FISH. In: Choo KHA, ed Methods in Molecular Biology: In situ hybridization protocols. p. 109-122. Clifton, New Jersey, Humana Press. Heng, H.H.Q., and Tsui, L-C. (1994). Chapter 4: FISH detection on DAPI banded chromosomes. In: Choo KHA, ed Methods in Molecular Biology: In situ hybridization protocols. p. 35-49. Clifton, New Jersey, Humana Press. Heng, H.H.Q., Tsui, L-C., Windle, B., and Parra, I. (1995). High-resolution FISH analysis. In: Dracopoli et al, ed Current Protocols for Human Genetics. p. 4.5.1-4.5.26. John Wiley & Sons, Inc. Heng, H.H.Q., Spyropoulos, B., and Moens, P. (1997). FISH technology in chromosome and genome research. BioEssays 19: 75-84. Heng, H.H.Q. and Shi X-M (1997). From free chromatin to fiber FISH. Cell Res 7: 119-124. Heng, H.H.Q., and Tsui, L-C. (1998). High resolution free chromatin/DNA fiber FISH. Invited review J of Chromatography 806: 219-229. Spyropoulos, B., Heng, H.H.Q., and Moens, P. (1997). Recycling Cells. TIG On line. Heng, H.H.Q, Spyropoulos, B., Moens, PB (1999). DNA-protein in situ co-detection. Methods in Molecular Biology: In situ hybridization protocols. Vol: 123: 15-27. Clifton, New Jersey, Humana Press. Heng, H.H.Q (1999). Released chromatin or DNA fiber preparation for high-resolution fiber FISH. Methods in Molecular Biology: In situ hybridization protocols. Vol: 123: 69-81. Clifton, New Jersey, Humana Press. Part B: Chromosomal Structure/function Studies Ye, J., Lu, W., Moens, P., Liu, G., Bremer, S., Wang Y, Hughes, M., Krawetz, S., and Heng, H.H.Q. (2001). The combination of SKY and specific loci detection with FISH or Immunostaining. Cytogenetics and Cell Genetics 93: 195-202. Heng, H.H.Q., Liu, G., Lu, W., Bremer, S., Ye C.J., Hughes, M., and Moens, P. (2001). Multicolor SKY painting of mouse meiotic chromosomes. Genome 44: 293-298. Heng, H.H.Q (2002). High resolution FISH mapping using chromatin and DNA fiber. In: Beatty et al ed, FISH: A Practical Approach. p.77-92. Oxford University Press. Heng, H.H.Q., Tsui, L-C., and Moens, P.B. (1994). Organization of heterologous DNA inserts on the mouse meiotic chromosome core. Chromosoma 103:401-407. Moens, P.B., Heng, H.H.Q., Pearlman, R.E., Rosonina, E., and Spyropoulos, B. (1995). Meiotic chromosomes visualized with antibodies and DNA probes. In KEW Chromosome Conference IV. Brandham and Bennett ed, pp. 375-379. Heng, H.H.Q., Chamberlain, J., Shi, X.M., Spyropoulos, B., Tsui, L-C., and Moens, P.B. (1996). Regulation of meiotic chromatin loop size by chromosomal position. Proc. Natl. Acad. Sci. USA 93: 2756-2800. Sam, M., Wurst, W., Forrester, L., Vauti, F., Heng, H.H.Q., and Bernstein, A. (1996). A novel family of repeat sequences in the mouse genome responsive to retinoic acid. Mammalian Genome 7: 741-748. Moens, P.B., Chen D.J., Shen, Z., Kolas, N., Tarsounas, M., Heng, H.H.Q., and Spyropoulos, B. (1997). Rad51 immunocytology in rat and mouse spermatocytes and oocytes. Chromosoma 106: 207-215. Heng, H.H.Q., Spyropoulos, B., and Moens, P.B. (1998). DNA-protein co-detection on meiotic chromosomes. Book chapter in Genome Analysis . Moens, P.B., Pearlman, R., Traut, W., and Heng, H.H.Q. (1997). Chromosome cores and chromatin at meiotic prophase. In Meiosis and GametogenesisCurrent topics in developmental biology Vol 37: 241-262. Moens, P.B., Heddle, J., Spyropoulos, B., and Heng, H.H.Q. (1997). Meiotic cytology of homologous sequences on non-homologous mouse chromosomes. Genome 40: 770-773. Part C: Analysis of Mitotic Chromosome/Genome/Interphase Nuclear Structure Heng, H.H.Q., Krawetz, SK., Lu, W., Bremer, S., Liu, G., and Ye, C.J. (2001). Re-defining the chromatin loop domain. Cytogent Cell Genet 93: 155-161 Schmid, C., Heng, H.H.Q., Rubin, C., Ye, C.J., and Krawetz, SK (2001). Sperm nuclear matrix of the PRM1-PRM2-TNP2 domain is independent of ALU methylation. Hum Mole Reproduction 7: 903-911. Heng, H.H.Q., Shi, X-M., Scherer, S., Andrulis, I.L., and Tsui, L-C. (1994). Refined localization of the asparagine synthetase gene locus (ASNS) to chromosome 7, region q21.3, and characterization of the somatic cell hybrid line 4AF/106/KO15. Cytogenet Cell Genet. 66: 135-138. Heng, H.H.Q., Xiao, H., Shi, X-M., Greenblatt, J., and Tsui, L-C. (1994). Genes encoding general initiation factors for RNA polymerase II transcription are dispersed in the human genome. Hum. Mol. Genetics. 3: 61-64. Kunz, J., Scherer, S., Klawitz, I., Soder, S., Du, Y-Z., Speich, N., Kalff-Suske, M., Heng, H.H.Q., Tsui, L-C., and Grzeschik, Karleinz. (1994). Regional localization of 725 human chromosome 7-specific yeast artificial chromosome clones. Genomics. 22: 439-448. Rozmahel, R., Heng, H.H.Q., Duncan, A.M.V., Shi, X-M., Rommens, J.M., and Tsui, L-C. (1997) Amplification of CFTR exon 9 sequences to mutiple locations in the human genome. Genomics 45: 554-561. Liu, G., Lu, W., Bremer, S., Hameister, H., Schreiner, B., Hughes, M., and Heng, H.H.Q. (2000). Spectral Karyotyping of Mouse Cell Line WMP2. Cytogenet Cell Genet 90: 271-274. Part D:Clinical/Developmental/Cancer Genetics Analysis and Disease Gene Cloning Wu, J., Salido, E.C., Yen, P.H., Mohandas, T.K., Heng, H.H.Q., Tsui, L-C., Park, J., Chapman, V.M., and Shapiro, L.J. (1994). The murine Xe169 gene escapes X-inactivation. Nature Genet 7: 491-496. Wu, H-K., Heng, H.H.Q., Forsdvke, D.R., Tsui, L-C., Mak, T.W., Minden, M.D., and Siderovski, D. (1995). Differential expression of a putative basic helix-loop-helix phosphoprotein gene, GOS8, in acute leukernia and localization to human chromosome 1q31. Leukemia 9:1291-1298. Petronis, A., Heng, H.H.Q., Tatuch, Y., Shi, X-M., Tsui, L-C., Ashizawa, T., Surh, L., and Kennedy, J. (1996). Direct detection of expanded trinucleotide repeats using DNA hybridization technique. Am J Med Genetics 67: 85-91. Wu, H-K., Heng, H.H.Q., Dong, W-F., Siderovaki, D.P., Shi, X-M., Okuno, Y., Tsui, L-C., and Minden, M.D (1996). Expression and chromosomal localization of a human LIM/HOX gene, hLH-2, in chronic myelogenous leukemia. Oncogene 12: 1205-1212. Osborne, L.R., Martindale, D., Scherer, S.W., Shi. X-M., Huizenga, J. Heng, H.H.Q., Costa, T., Pober, B., Lew, L., Brinkman, J., Rommens, J., Koop, B., and Tsui, L-C. (1996). Identification of genes from a 500 kb region at 7q11.23 that is commonly deleted in Williams syndrome patients. Genomics 36: 328-336. Mo, R., Freer, A.M., Zinyk, D.L., Crackower, M.A., Michaud, J., Heng, H.H.Q., Chik. K.W., Shi, X-M., Tsui, L-C., Cheng, S-H., Joyner, A.L., and Hui, C-C. (1997). Development 124: 113-123. Wang, A., Forman-Kay, J., Lou, Y., Chow, Y-H., Plumb, J., Friesen, J., Tsui, L-C., Heng, H.H.Q., Woolford, J., and Hu, J. (1997). Identification and characterization of human genes encoding Hprp3p and Hprp4p, interacting components of the slicesome. Hum Mole Genet 6: 2117-2126. Belloni, E., muenke, M., Roessler, E., Traverso, G., Siegel-Bartelt, J., Frumkin, A., Mitchell, H., Donis-Keller, H., Helms, C., Heng, H.H.Q., Koop, B., Martindale, D., Rommens, J., Tsui, L-C., and Scherer SW. (1996). Identification of Sonic hedgehog as a candidate gene responsible for holoprosencephaly. Nature Genet 14; 353-356. Part E: Gene/Physical Mapping (human and mouse) and Gene Therapy Studies Ding, B.C., Witt, T.L., Hukku, B., Heng, H., Zhang, L., and Matherly, L.H. (2001). Deletions and translocations of the reduced folate carrier gene are associate with profound loss of gene expression in methotrexate resistant K562 human erythroleukemia cells. Biochem. Pharmacol 61: 665-675. Dong, S., Leung, KKH., Pelling, A.L., Lee, PYT., Tang, A., Heng, HHQ., Tsui, L-C., Tease, C., Fisher, G., Stell, K.P., and Cheah, KSE (2002). Circling, deafness and yellow coat colour displayed by the chromosome 3 mouse mutant yellow submarine (Ysb) and light coat circling (Lcc). Genomics 79(6):777-84. Shekhar, M.P.V., Lyakhovich, A., Visscher, D. W., Heng, H., and Kondrat, N. (2002). Rad 6 overexpression induces multinucleation, centrosome amplification, abnormal mitotic, aneuploidy, and transformation. Cancer Research 62: 2115-2124. Heng, H.H.Q., Shi, X-M., and Tsui, L-C. (1993). Fluorescence in situ hybridization mapping of the cystic fibrosis transmembrane conductance regulator (CFTR) gene to 7q31.3. Cytogenet Cell Genet. 62: 108-109. Heng, H.H.Q., Xie, B., Shi, X-M., Tsui, L-C., and Mahuran, D. J. (1993). Refined mapping of the Gm2 activator protein (GM2A) locus to 5q31.3-q33.1, distal to the spinal muscular atrophy locus. Genomics 18: 429-431. Marsden, P.A., Heng, H.H.Q., Scherer, S., Stewart. R.J., Hall. A.V., Shi, X-M., Tsui, L-C., and Schappert, K.T. (1993). Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene. J. Biol. Chem. 268: 17478-17488. O'Dowd, B., Heiber, M., Chan, A., Heng, H.H.Q., Tsui, L-C., Kennedy, J., Shi, X-M., Petronis, A and Nguyen, T. (1993) A human intronless gene with homology to the angiotensin receptor gene is located on chromosome 11. Gene 136: 355-360. Ali, S.T., Duncan, M.V., Schappert, K., Heng, H.H.Q., Tsui, L-C., Chow, W., and Robinson, B.H. (1993). Chromosomal localization of the human gene encoding the 51-kDa subunit of mitochondrial complex I (NDUFV1) to 11q13. Genomics 18: 435-439. Heiber, M., Docherty, J., Nguyen, T., Cheng, R., Heng, H.H.Q., Marchese, A., Tsui, L-C., Shi, X.M., George, S.R., and O'Dowd, B.F. (1994). Isolation of three novel human genes encoding G protein-coupled receptors. DNA and Cell Biology 14:25-35. Marsden, P., Heng, H.H.Q., Duff, C., Shi, X-M., Tsui, L-C., and Hall, A. (1994). Localization of the human gene for inducible nitric oxide synthase to chromosome 17q11.2-12. Genomics 19: 183-185. Marchese, A., Docherty, J., Nguyen, T., Heiber, M., Cheng, R., Heng, H.H.Q., Tsui, L-C., Shi, X-M., George, S.R., and O'Dowd, B.F. (1994). Cloning of human genes encoding novel G protein-coupled receptors. Genomics 23:609-618. Ing, L., Leung, I., Heng, H.H.Q., Tsui, L-C., and Lassam, N.J. (1994). MLK-3: identification of a widely-expressed protein kinase bearing an SH3 domain and a leucine zipper-basic region domain. Oncogene 9: 1745-1750. Feng, G-S., Shen, R., Heng, H.H.Q., Tsui, L-C., Kazlauskas, A., and Pawson, T. (1994). Receptor-binding, tyrosine phosphorylation and chromosome localization of the mouse SH2-containing phosphotyrosine phosphatase Syp. Oncogene 9: 1545-1550. Zhang, X-L., Lee, K-L., Heng, H.H.Q., and Tsui, L-C., Parnes, J.R., Stepherd, N.S., and Chamberlain, J. (1995). Isolation of P1 bacteriophage clones containing large contiguous segments of the human and mouse loci for the T cell co-receptor molecule CD8. GAGT 11: 129-139. Charest, A., Wagner, J., Muise, E., Heng, H.H.Q., and Tremblay, M. (1995). Structure of the murine MPTP-PEST gene: Genomic organization and chromosomal mapping. Genomics 28: 501-507. Barron-Casella, E.A., Scherer, S., Heng, H.H.Q., Tsui, L-C., and Casella, J.F. (1995). Sequence analysis of human Cap Z : functional conservation of an actin-binding domain. J. Biol. Chem. 270: 21472-21479. Scherer, S.W., Heng, H.H.Q., Mahon, K.A., Evans, J., and Tsui, L-C. (1995). Assignment of the human homolog of mouse DIX-3 to chromosome 17q21-q22 by analysis of somatic cell hybrids and fluorescent in situ hybridization. Mammal genome 6: 310-311. Marchese, A., Heiber, M., Nguyen, T., Heng, H.H.Q., Saldivia, V., Cheng, R., Murphy, P., Tsui, L-C., Shi, X.M., Gergor, P., George, S.R., and O'Dowd, B.F., and Docherty, J., (1995). Cloning and chromosomal mapping of three novel genes, GPR9, GPR10, and RPR14, encoding receptors related to interleukin 8, neuropeptide Y, and somatostatin receptors. Genomics 29: 335-344. Huang, F., Shi, L-J., Heng, H.H.Q., Fei, J., and Guo, L-H. (1995). Assignment of the human GABA transporter gene (GABATHG) locus to chromosome 3p24-p25. Genomics 29: 302-304. Fung, Y-W., Wang, R-X., Heng, H.H.Q., and Liew, C.C. (1995). Mapping of a human LIM protein (CLP) to human chromosome 11p15.1 by fluorescence in situ hybridization. Genomics 28: 602-603. O'Dowd, B., Scheideler, M., Nguyen, T., Cheng, R., Rasmussen, J.S., Marchese, A., Zastawny, R., Heng, H.H.Q, Tsui, L-C., Shi, X-M., Asa, S., Puy, L and George, S. (1995). The cloning and chromosomal mapping of two novel human opioid-somatostatin-like receptor genes, GPR7 and GPR8, expressed in Discrete areas of the brain. Genomics 28: 84-91. Zhang, X-Y., Heng, H.H.Q., Yang, Y., Tsui, L-C., Parnes, J.R., and Chamberlin, J.W. (1996). Immunogenetics 43: 220-228. Heiber, M., Marchese, A., Nauyen, T., Heng, H.H.Q., George, S., and O'Down, B. (1996). A novel human gene encoding a G-protein-coupled receptor (RPR 15) is located on chromosome 3. Genomics 32: 463-465. Huang, W-Y., Heng, H.H.Q., and Liew, C.C. (1996). Assignment of the human GATA 4 gene to 8p23.2-p22 using fluorescence in situ hybridization analysis. Cytogenet Cell Genet 72: 217-218. Nguyen, T., Erb, L., Weisman, G.R., Marchese, A., Heng, H.H.Q., Garrad, R., George, S., Turner, J., and O'Dowd, B. (1995). Cloning, expression, and chromosomal localization of the human uridine nucleotide receptor gene. J. Biol. Chem. 270: 30845-30848. Scherer, S., Duvoisin, R.M., Kuhn, R., Heng, H.H.Q., Belloni, E., and Tsui, L-C. (1995). Localization of two metabotropic glutamate receptor genes, GRM 3 and GRM 8, to human chromosome 7q. Genomics 31: 230-233. Malaney, S., Heng, H.H.Q., Tsui, L-C., Shi, X.M., Robinson, B.H., and Ozawa, T. (1996). Chromosomal localization of the human gene encoding the 14-kDa ubiquinone binding protein of mitochondrial complex III to 8q22. Cytogent Cell Genet 73: 297-299. Xie, Y., and Heng, H.H.Q. (1996). FISH mapping of CENP-C on human chromosome 4, region q13-q21. Cytogent Cell Genet 74: 192-193. Yang, B.Z., Heng, H.H.Q., Ding, J.H., and Roe, C.R. (1996). The gene for the alpha and beta subunits of the mitochondrial trifunctional protein are both located in the same region of human chromosome 2p23. Genomics 37: 141-143. Kim, K.K., Youn, B-S., Heng, H.H.Q., Shi, X.M., Tsui, L-C., Lee, Z.H., and Pickard, R.T. (1996) Genomic organization and FISH mapping of human PMEL 17, the putative silver locus. Pigment Cell Res 9: 42-49. Tsukiyama-Kohara, K., Vidal, S., Gingras, A. C., Glover, T., Hanash, S., Heng H.H.Q., and Sonenberg, N. (1996). Tissue distribution, genomic structure, and chromosome mapping of mouse and human eukaryotic initiation factor 4E-binding proteins 1 and 2. Genomics 38: 353-363. Wang, R., Cukerman, E., Heng, H.H.Q., and Liew, C.C. (1996). Localization of three novel zinc figer genes to the centromeric region of human chromosome 10 by FISH. Somatic Cell and Mol Genet 22: 241-244. Wang, R., Cukerman, E., Heng, H.H.Q., and Liew, C.C. (1996). Localization of a novel zinc figer gene to human chromosome 7p11.2-p12 by FISH. Somatic Cell and Mol Genet 22: 237-239. Wagner, J., Gordon, L.A., Heng, H.H.Q., Tremblay, M., and Olsen, A.S. (1996). Physical mapping of receptor type protein tyrosine phosphatase sigma (PTPRS) to human chromosome 19p13.3. Genomics 38: 76-80. Wang, R., Cukerman, E., Heng, H.H.Q., and Liew, C.C. (1996). Localization of a locus of zinc figer gene to human chromosome 19q13.1-q13.3 region by FISH. Somatic Cell and Mol Genet 22: 245-248. Wang, R., Cukerman, E., Heng, H.H.Q., and Liew, C.C. (1996). Localization of a locus of zinc figer gene to human chromosome. Somatic Cell and Mol Genet 22: 233-235. Dong, W.F., Wu, H.K., Xu, Y.L., Heng, H.H.Q., Tsui, L-C., and Mioden, M. (1997). Cloning, characterization and chromosomal mapping of human LIH-1. DNA and Cell Biology 16: 671-678. O'Dowd, B., Nguyen, B., Lynch, K., Kolakowski, L.,Marchese, A., Ng, G., Heng, H.H.Q., George, S. (1996). A novel gene codes for a putative G-protein-coupled receptor with an aboundant expression in brain. FEBS 394: 325-329. Kolakowski, L., Jung, B., Nguyen, T., Hohnson, M., Lynch, K., Cheng, R., Heng, H.H.Q., George, S., and O'Down, B. (1996). Characterization of a human gene related to genes encoding somatostatin receptors. FEBS 398: 253-258. O'Down, B., Nguyen, T., Jung, B., Marchese, A., Cheng, R., M., Heng, H.H.Q., Kolakowski, L., Lynch, K., and George, S. (1997). Cloning and chromosomal mapping of four putative novel human G-protein-coupled receptor genes. Gene 187: 75-81. Cohen, D., Heng, H.H.Q., Shi, X-M., Mclntosh, E., Tsui, L-C., and Pearlman, R. (1997). Assignment of the human dUTPase gene (DUT) to chromosome 15q15-q21.1 by fluorescence in situ hybridization. Genomics 40: 213-215. Jung, B., Nguyen, T., Kolakowski, L., Lynch, K., Heng, H.H.Q., George, S., and O'Dowd, B. (1997). Discovery of a novel human G protein-coupled receptor gene (RPR25) located on chromosome 1. BBRC 230: 69-72. Crackower, M.A., Scherer, S.W., Heng, H.H.Q., and Tsui, L-C. (1997). Cloning of a DSS1 pseudogene (DSS1P1) and mapping to human chromosome band 5q14. Mammal Genome 159-160. Liu, L., Zhao, C., Heng, H.H.Q., and Ganz, T. (1997). The Human b-Defensin-1 and a-Defensins Are Encoded by Adjacent Genes: Two Peptide Families with Differing Disulfide Topology Share a Common Ancestry. Genomics 43: 316-320. Crackower, M.A., Heng, H.H.Q., Shi, X-M., Scherer, S.W., and Tsui, L-C. (1997). Mapping of mouse Dss1 gene. Mammal Genome (in press). Snow, B., Heng, HHQ., Shi, XM, Zhou, Y., Du, K., Taub, R., Tsui, L-C., and Mcinnes, R., (1997). Genomics 43: 165. Okana K., Heng, H.H.Q., Trevisanato, Tyers M,m and Varmuza, S. (1997). Genomic organization and functional analysis of the murine protein phosphatase 1 c (Ppp1cc) gene. Genomics 45: 211-215. Heng, H.H.Q., Wang, A., anf Hu, J. (1998). Mapping of the human HPRP3 and HPRP4 encoding U4/U6- associated splicing factors to chromosome 1q21.1 and chromosome 9q31-q33. Genomics 48:273-275. Osborne, L., Herbrick, J., Greavette, T., Heng, H.H.Q., Tsui, L-C., and Scherer, WS. (1997). PMS2-related genes (hPMSR) flank the Williams syndrome deletion and are near other disease-associated rearrangement breakpoints on chromosome 7. Genomics 45: 402-406. Takeuchia, T., Furihataa, M., Heng, H.H.Q., Sonobea, H., and Ohtsukia, Y. (1998). Chromosomal mapping and expression of human B120 gene. Gene 213: 189-193. Pimemta, A., Tsui. L-C., Heng, H.H.Q., and Levitt, P. (1998). Assignment of the gene encoding the limbie system-associated membrane protein (LAMP) to mouse chromosome 16B5 and human chromosome 3q13.2-q21. Genomics 49:472-474. 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